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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sanchez, Adan | C | Augusta GreenJackets | 18 | 05/24/2005 | Panama | PAN | Right | Right | 6' 0" | 205 lbs | - |
| Sanchez, Axel | 3B | San Jose Giants | 20 | 12/10/2002 | Santo Domingo | DOM | Right | Right | 6' 0" | 170 lbs | - |
| Sandridge, Jayvien | RP | Delmarva Shorebirds | 24 | 02/11/1999 | Hagerstown | USA | Left | Left | 6' 5" | 220 lbs | - |
| Sanquintin, Junior | SS | Stockton Ports | 21 | 01/08/2002 | Baní | DOM | Switch | Right | 6' 0" | 185 lbs | - |
| Sansone, Michael | SP | Rancho Cucamonga Quakes | 23 | 11/10/1999 | Cheshire | USA | Right | Left | 5' 8" | 170 lbs | - |
| Santana, Debby | 3B | Augusta GreenJackets | 23 | 08/24/2000 | Sabana Grande de Palenque | DOM | Right | Right | 6' 2" | 185 lbs | - |
| Santana, Ruben | 3B | Lynchburg Hillcats | 18 | 02/16/2005 | El Seibo | DOM | Right | Right | 6' 0" | 190 lbs | - |
| Santos, Alex | SP | Columbia Fireflies | 21 | 02/10/2002 | New York | USA | Right | Right | 6' 3" | 195 lbs | - |
| Santos, Ghordy | 2B | Fort Myers Mighty Mussels | 24 | 09/02/1999 | San Pedro de Macorís | DOM | Switch | Right | 6' 1" | 175 lbs | - |
| Santos, Junior | SP | Jupiter Hammerheads | 22 | 08/16/2001 | Santiago | DOM | Right | Right | 6' 8" | 220 lbs | - |
| Santos, Lisandro | RP | Down East Wood Ducks | 25 | 07/24/1998 | Santiago | DOM | Left | Left | 6' 1" | 170 lbs | - |
| Santos, Madison | CF | Salem Red Sox | 24 | 09/06/1999 | Monte Cristi | DOM | Left | Right | 5' 10" | 165 lbs | - |
| Saucedo, Tayler | RP | Free Agent | 30 | 06/18/1993 | Honolulu | USA | Left | Left | 6' 5" | 185 lbs | - |
| Savino, Nate | SP | Carolina Mudcats | 21 | 01/24/2002 | Sterling | USA | Left | Left | 6' 3" | 215 lbs | - |
| Scalzo Jr., Frankie | CL | Fayetteville Woodpeckers | 23 | 11/25/1999 | Vista | USA | Right | Right | 6' 3" | 190 lbs | - |
| Schaeffer, Brandon | SP | Salem Red Sox | 24 | 06/05/1999 | Unknown | USA | Left | Left | 6' 2" | 195 lbs | - |
| Schultz, Noah | SP | Columbia Fireflies | 20 | 08/05/2003 | Aurora | USA | Left | Left | 6' 9" | 225 lbs | - |
| Scott, Christian | SP | Myrtle Beach Pelicans | 24 | 06/15/1999 | Parkland | USA | Right | Right | 6' 4" | 180 lbs | - |
| Scott, Tayler | RP | Free Agent | 31 | 06/01/1992 | Johannesburg | RSA | Right | Right | 6' 3" | 185 lbs | - |
| Selma, Quentin | 1B | Free Agent | 25 | 06/08/1998 | Clovis | USA | Left | Right | 6' 3" | 205 lbs | - |
| Selman, Sam | RP | Free Agent | 32 | 11/14/1990 | Austin | USA | Right | Left | 6' 3" | 190 lbs | - |
| Selvidge, Brock | RP | Salem Red Sox | 21 | 08/28/2002 | Chandler | USA | Right | Left | 6' 3" | 200 lbs | - |
| Sequeira, Gabriel | RP | Bradenton Marauders | 26 | 08/18/1997 | Dallas | USA | Left | Left | 6' 0" | 205 lbs | - |
| Serrano, Florencio | RP | Tampa Tarpons | 23 | 02/23/2000 | Corpus Christi | USA | Right | Right | 6' 2" | 210 lbs | - |
| Serrano, Jose | SS | Carolina Mudcats | 20 | 10/14/2003 | San Fernando | VEN | Right | Right | 6' 0" | 180 lbs | - |
| Servideo, Anthony | SS | Lake Elsinore | 24 | 03/11/1999 | Jupiter | USA | Left | Right | 5' 11" | 170 lbs | - |
| Severino, Jhonny | 3B | Jupiter Hammerheads | 18 | 11/08/2004 | Santo Domingo | DOM | Right | Right | 6' 3" | 185 lbs | - |
| Short, Avery | RP | Charleston RiverDogs | 22 | 03/14/2001 | Indianapolis | USA | Right | Left | 6' 1" | 205 lbs | - |
| Sierra, Jonathan | LF | Modesto Nuts | 25 | 10/17/1998 | Santo Domingo | DOM | Left | Left | 6' 3" | 190 lbs | - |
| Sightler, Josiah | SP | Stockton Ports | 24 | 10/19/1999 | Gaston | USA | Left | Left | 6' 5" | 235 lbs | - |
| Simonelli, Anthony | RP | Free Agent | 24 | 12/23/1998 | Winchester | USA | Right | Right | 6' 2" | 200 lbs | - |
| Simpson, Chandler | 2B | Modesto Nuts | 22 | 11/18/2000 | East Point | USA | Left | Right | 6' 2" | 170 lbs | - |
| Sinacola, Nick | SP | Dunedin Blue Jays | 24 | 10/29/1999 | Unknown | USA | Left | Right | 6' 1" | 190 lbs | - |
| Skirrow, Noah | SP | Delmarva Shorebirds | 25 | 07/21/1998 | Hamilton | CAN | Right | Right | 6' 3" | 215 lbs | - |
| Skoug, Evan | C | Free Agent | 28 | 10/21/1995 | Libertyville | USA | Left | Right | 5' 11" | 200 lbs | - |
| Smith, Austin | RP | Lynchburg Hillcats | 24 | 06/22/1999 | Cedar Park | USA | Right | Right | 6' 3" | 170 lbs | - |
| Smith, Jake | RP | Fort Myers Mighty Mussels | 24 | 10/04/1999 | Chapel Hill | USA | Right | Right | 6' 4" | 190 lbs | - |
| Smith, Marcus | LF | Carolina Mudcats | 23 | 09/11/2000 | Kansas City | USA | Left | Left | 5' 11" | 190 lbs | - |
| Smith, Russell | SP | Columbia Fireflies | 25 | 09/10/1998 | Midlothian | USA | Left | Left | 6' 9" | 235 lbs | - |
| Smith2, Kevin | RP | Carolina Mudcats | 26 | 05/13/1997 | Dunwoody | USA | Right | Left | 6' 5" | 200 lbs | - |
| Snelling, Robby | SP | Carolina Mudcats | 19 | 12/19/2003 | Reno | USA | Right | Left | 6' 3" | 220 lbs | - |
| Snider, Jake | 1B | Free Agent | 25 | 05/19/1998 | Champaign | USA | Left | Right | 5' 11" | 185 lbs | - |
| Solarte, Angel | CF | Daytona Tortugas | 22 | 03/29/2001 | Unknown | VEN | Right | Right | 5' 11" | 155 lbs | - |
| Soles, Lemuel | LF | Lynchburg Hillcats | 19 | Unknown | USA | Right | Right | 0' 0" | 0 lbs | - | |
| Solometo, Anthony | SP | Salem Red Sox | 20 | 12/02/2002 | Unknown | USA | Left | Left | 6' 4" | 200 lbs | - |
| Soto, Franklin | 2B | Rancho Cucamonga Quakes | 24 | 09/23/1999 | San Cristóbal | DOM | Right | Right | 5' 11" | 170 lbs | - |
| Sotolongo, Adriel | 3B | Carolina Mudcats | 25 | 04/22/1998 | Havana | CUB | Right | Right | 6' 3" | 205 lbs | - |
| Specht, Tommy | RF | Daytona Tortugas | 19 | 06/24/2004 | Dubuque | USA | Left | Right | 6' 2" | 190 lbs | - |
| Spence, Liam | SS | Bradenton Marauders | 25 | 04/09/1998 | Geelong | AUS | Right | Right | 6' 1" | 190 lbs | - |
| Spikes, Ryan | SS | Fredericksburg Nationals | 20 | 03/13/2003 | Covington | USA | Right | Right | 5' 9" | 180 lbs | - |
| Spitzbarth, Shea | RP | Free Agent | 29 | 10/04/1994 | New York | USA | Right | Right | 6' 1" | 195 lbs | - |
| Spohn, Harrison | 3B | Delmarva Shorebirds | 24 | 12/03/1998 | Upland | USA | Right | Right | 6' 3" | 185 lbs | - |
| Stanavich, Dale | RP | Fort Myers Mighty Mussels | 24 | 06/23/1999 | Amsterdam | USA | Left | Left | 5' 11" | 175 lbs | - |
| Stankiewicz, John | SP | Modesto Nuts | 25 | 09/08/1998 | Cherry Hill | USA | Right | Right | 6' 4" | 230 lbs | - |
| Stefanic, Michael | 2B | St. Lucie Mets | 27 | 02/24/1996 | Teutopolis | USA | Right | Right | 5' 10" | 180 lbs | - |
| Steinmetz, Jacob | SP | Bradenton Marauders | 20 | 07/19/2003 | Woodmere | USA | Right | Right | 6' 6" | 220 lbs | - |
| Stephen, Josh | LF | Free Agent | 26 | 09/22/1997 | Newport Beach | USA | Left | Left | 6' 0" | 185 lbs | - |
| Stevens, Felix | LF | Stockton Ports | 24 | 07/30/1999 | Havana | CUB | Right | Right | 6' 4" | 235 lbs | - |
| Stewart, Brock | SP | Palm Beach Cardinals | 32 | 10/03/1991 | Normal | USA | Left | Right | 6' 3" | 215 lbs | - |
| Stewart, Sal | 3B | Lynchburg Hillcats | 19 | 12/07/2003 | Miami | USA | Right | Right | 6' 3" | 215 lbs | - |
| Stewart, Will | SP | Free Agent | 26 | 07/14/1997 | Hazel Green | USA | Left | Left | 6' 2" | 175 lbs | - |
| Stivors, Tristan | RP | Delmarva Shorebirds | 25 | 09/22/1998 | Hondo | USA | Right | Right | 6' 4" | 200 lbs | - |
| Stuart, Tyler | RP | Fort Myers Mighty Mussels | 24 | 10/08/1999 | Kankakee | USA | Right | Right | 6' 9" | 235 lbs | - |
| Suarez, Albert | 2B | Delmarva Shorebirds | 23 | 11/30/1999 | San Pedro de Macorís | DOM | Left | Right | 5' 11" | 150 lbs | - |
| Sublette, Ryan | RP | Daytona Tortugas | 25 | 10/01/1998 | Lemont | USA | Right | Right | 6' 2" | 200 lbs | - |
| Susac, Daniel | C | Carolina Mudcats | 22 | 05/14/2001 | Roseville | USA | Switch | Right | 6' 4" | 205 lbs | - |
| Swanson, Nic | SP | Rancho Cucamonga Quakes | 24 | 07/08/1999 | Bixby | USA | Right | Right | 6' 2" | 180 lbs | - |
