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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salazar, Alejandro | 2B | Nashville Sounds | 24 | 10/05/1996 | Cabimas | VEN | Right | Right | 6' 0" | 170 lbs | - |
| Sanchez, Jesus Armando | RF | Sacramento River Cats | 23 | 10/07/1997 | Higüey | DOM | Left | Right | 6' 3" | 230 lbs | $545,000 |
| Sanchez, Sixto | RP | Salt Lake Bees | 22 | 07/29/1998 | San Cristóbal | DOM | Right | Right | 6' 0" | 185 lbs | $545,000 |
| Sanchez, Yolbert | SS | Albuquerque Isotopes | 23 | 03/03/1997 | Havana | CUB | Right | Right | 5' 11" | 175 lbs | - |
| Sandberg, Cord | RF | Free Agent | 25 | 01/02/1995 | Bradenton | USA | Left | Left | 6' 3" | 215 lbs | - |
| Santana, Edgar | RP | Louisville Bats | 29 | 10/16/1991 | Puerto Plata | DOM | Right | Right | 6' 2" | 190 lbs | $545,000 |
| Santillan, Tony | RP | Sacramento River Cats | 23 | 04/15/1997 | Arlington | USA | Right | Right | 6' 3" | 240 lbs | $545,000 |
| Santos, Antonio | RP | Salt Lake Bees | 24 | 10/06/1996 | Villa Gonzalez | DOM | Right | Right | 6' 3" | 180 lbs | - |
| Sawyer, Dalton | SP | Louisville Bats | 26 | 11/22/1993 | Waconia | USA | Left | Left | 6' 5" | 210 lbs | - |
| Sawyer, Wynston | C | Free Agent | 28 | 11/14/1991 | San Diego | USA | Right | Right | 6' 3" | 215 lbs | - |
| Scavuzzo, Jacob | LF | Free Agent | 26 | 01/15/1994 | East Orange | USA | Right | Right | 6' 4" | 185 lbs | - |
| Scheetz, Kit | RP | Norfolk Tides | 26 | 05/18/1994 | Richmond | USA | Left | Left | 5' 10" | 185 lbs | - |
| Scheiner, Jake | 3B | Norfolk Tides | 25 | 08/13/1995 | Santa Rosa | USA | Right | Right | 6' 1" | 200 lbs | - |
| Schellenger, Zach | RP | Gwinnett Stripers | 24 | 01/09/1996 | Malvern | USA | Right | Right | 6' 5" | 210 lbs | - |
| Schick, Alex | RP | Tacoma Rainiers | 25 | 12/01/1994 | San Diego | USA | Right | Right | 6' 7" | 210 lbs | - |
| Schrock, Max | 2B | El Paso Chihuahuas | 26 | 10/12/1994 | Chapel Hill | USA | Left | Right | 5' 9" | 195 lbs | - |
| Schultz, Jaime | RP | Free Agent | 29 | 06/20/1991 | Albany | USA | Right | Right | 5' 10" | 205 lbs | - |
| Schwindel, Frank | 1B | Colorado Springs Sky Sox | 28 | 06/29/1992 | Livingston | USA | Right | Right | 6' 1" | 215 lbs | $545,000 |
| Scott, Adam | SP | Round Rock Express | 25 | 10/10/1995 | Canandaigua | USA | Left | Left | 6' 4" | 220 lbs | - |
| Seabold, Connor | SP | Salt Lake Bees | 24 | 01/24/1996 | Newport Beach | USA | Right | Right | 6' 2" | 190 lbs | - |
| Sears, JP | SP | Iowa Cubs | 24 | 02/19/1996 | Sumter | USA | Right | Left | 5' 11" | 180 lbs | - |
| Segedin, Rob | 3B | Memphis Redbirds | 31 | 11/10/1988 | Teaneck | USA | Right | Right | 6' 2" | 220 lbs | - |
| Semple, Shawn | SP | Memphis Redbirds | 25 | 10/09/1995 | Swedesboro | USA | Right | Right | 6' 1" | 220 lbs | - |
| Senzel, Nick | 3B | Memphis Redbirds | 25 | 06/29/1995 | Knoxville | USA | Right | Right | 6' 1" | 205 lbs | $545,000 |
| Severino, Pedro | C | Las Vegas 51s | 27 | 07/20/1993 | Bonao | DOM | Right | Right | 6' 1" | 220 lbs | - |
| Shaffer, Brian | SP | Gwinnett Stripers | 24 | 08/12/1996 | Baltimore | USA | Right | Right | 6' 5" | 200 lbs | - |
| Sharpe, Chris | LF | Iowa Cubs | 24 | 06/06/1996 | Burlington | USA | Right | Right | 6' 1" | 195 lbs | - |
| Sharpe, John | 2B | Free Agent | 24 | 02/28/1996 | Knoxville | USA | Right | Right | 6' 1" | 170 lbs | - |
| Shaw, Chris | 1B | Toledo Mud Hens | 26 | 10/20/1993 | Lexington | USA | Left | Right | 6' 3" | 225 lbs | $545,000 |
| Shawaryn, Mike | SP | Round Rock Express | 26 | 09/17/1994 | Carneys Point | USA | Right | Right | 6' 2" | 200 lbs | - |
| Shepherd, Chandler | SP | Columbus Clippers | 28 | 08/25/1992 | Louisa | USA | Right | Right | 6' 3" | 185 lbs | - |
| Shetter, Ryan | RP | Pawtucket Red Sox | 23 | 03/05/1997 | Friendswood | USA | Right | Right | 6' 3" | 205 lbs | - |
| Shew, Anthony | SP | Fresno Grizzlies | 26 | 11/03/1993 | Brookings | USA | Right | Right | 6' 2" | 205 lbs | - |
| Shewmake, Braden | 2B | Toledo Mud Hens | 22 | 11/19/1997 | Wylie | USA | Left | Right | 6' 4" | 190 lbs | - |
| Shipley, Braden | SP | Free Agent | 28 | 02/22/1992 | Medford | USA | Right | Right | 6' 1" | 190 lbs | - |
| Shore, Logan | RP | Reno Aces | 25 | 12/28/1994 | Coon Rapids | USA | Right | Right | 6' 2" | 215 lbs | - |
| Shreve, Chasen | RP | Tacoma Rainiers | 30 | 07/12/1990 | Las Vegas | USA | Left | Left | 6' 4" | 195 lbs | $1,155,000 |
| Shuck, JB | LF | Louisville Bats | 33 | 06/18/1987 | Westerville | USA | Left | Left | 5' 11" | 195 lbs | - |
| Sierra, Magneuris | C | Toledo Mud Hens | 24 | 04/07/1996 | San Cristóbal | DOM | Left | Left | 5' 11" | 160 lbs | $545,000 |
| Sierra, Yaisel | CL | Pawtucket Red Sox | 29 | 06/05/1991 | Holguín | CUB | Right | Right | 6' 1" | 170 lbs | - |
| Sims, Lucas | SP | Norfolk Tides | 26 | 05/10/1994 | Lawrenceville | USA | Right | Right | 6' 2" | 225 lbs | $545,000 |
| Singer, Brady | SP | Omaha Storm Chasers | 24 | 08/04/1996 | Leesburg | USA | Right | Right | 6' 5" | 210 lbs | - |
| Siri, Jose | CF | Louisville Bats | 25 | 07/22/1995 | Sabana Grande de Boya | DOM | Right | Right | 6' 2" | 175 lbs | $545,000 |
| Sisco, Chance | C | New Orleans Baby Cakes | 25 | 02/24/1995 | Corona | USA | Left | Right | 6' 2" | 195 lbs | $545,000 |
| Skole, Matt | 3B | Toledo Mud Hens | 31 | 07/30/1989 | Woodstock | USA | Left | Right | 6' 4" | 220 lbs | - |
| Skubal, Tarik | SP | Oklahoma City Dodgers | 23 | 11/20/1996 | Kingman | USA | Left | Left | 6' 3" | 215 lbs | - |
| Slegers, Aaron | SP | Free Agent | 28 | 09/04/1992 | Scottsdale | USA | Right | Right | 6' 10" | 245 lbs | - |
| Smith, Carson | RP | Tacoma Rainiers | 31 | 10/19/1989 | Midland | USA | Right | Right | 6' 6" | 215 lbs | $2,250,000 |
| Smith, Kevin | RP | Sacramento River Cats | 23 | 05/13/1997 | Dunwoody | USA | Right | Left | 6' 5" | 200 lbs | - |
| Smith, Marcus | CF | Colorado Springs Sky Sox | 20 | 09/11/2000 | Kansas City | USA | Left | Left | 5' 11" | 190 lbs | - |
| Smith, Pavin | 1B | Reno Aces | 24 | 02/06/1996 | Jupiter | USA | Left | Left | 6' 2" | 210 lbs | - |
| Smith, Ridge | C | Free Agent | 25 | 04/26/1995 | Germantown | USA | Right | Right | 5' 10" | 190 lbs | - |
| Smith Jr., Dwight | LF | El Paso Chihuahuas | 27 | 10/26/1992 | Peachtree City | USA | Left | Right | 6' 0" | 210 lbs | $545,000 |
| Smoker, Josh | RP | Free Agent | 31 | 11/26/1988 | Calhoun | USA | Left | Left | 6' 1" | 230 lbs | - |
| Smolinski, Jake | CF | Free Agent | 31 | 02/09/1989 | Rockford | USA | Right | Right | 5' 11" | 205 lbs | - |
| Sneed, Cy | SP | Buffalo Bisons | 28 | 10/01/1992 | Twin Falls | USA | Right | Right | 6' 4" | 215 lbs | $950,000 |
| Soto, Gregory | RP | Reno Aces | 25 | 02/11/1995 | Bajos de Haina | DOM | Left | Left | 6' 1" | 240 lbs | $545,000 |
| Sousa, Bennett | RP | Durham Bulls | 25 | 04/06/1995 | North Palm Beach | USA | Left | Left | 6' 3" | 185 lbs | - |
| Sparkman, Glenn | SP | Rochester Red Wings | 28 | 05/11/1992 | Ganado | USA | Right | Right | 6' 2" | 210 lbs | $545,000 |
| Spear, Nick | RP | Nashville Sounds | 24 | 06/05/1996 | Atlanta | USA | Right | Right | 5' 11" | 175 lbs | - |
| Stammen, Craig | RP | Sacramento River Cats | 36 | 03/09/1984 | Coldwater | USA | Right | Right | 6' 4" | 230 lbs | - |
| Stanek, Ryne | CL | Oklahoma City Dodgers | 29 | 07/26/1991 | Overland Park | USA | Right | Right | 6' 4" | 225 lbs | $545,000 |
| Stankiewicz, Drew | 2B | Durham Bulls | 27 | 06/18/1993 | Gilbert | USA | Left | Right | 5' 9" | 160 lbs | - |
| Stapler, Cole | SP | Columbus Clippers | 25 | 12/22/1994 | Gonzales | USA | Right | Right | 6' 4" | 240 lbs | - |
| Stashak, Cody | RP | Rochester Red Wings | 26 | 06/04/1994 | Somers Point | USA | Right | Right | 6' 2" | 170 lbs | - |
| Staumont, Josh | RP | Toledo Mud Hens | 26 | 12/21/1993 | La Mirada | USA | Right | Right | 6' 3" | 200 lbs | - |
| Steckenrider, Drew | RP | El Paso Chihuahuas | 29 | 01/10/1991 | Atlanta | USA | Right | Right | 6' 5" | 215 lbs | $1,090,000 |
| Stevenson, Andrew | LF | Norfolk Tides | 26 | 06/01/1994 | Lafayette | USA | Left | Left | 6' 0" | 190 lbs | $545,000 |
| Stevenson, Cal | LF | Albuquerque Isotopes | 24 | 09/12/1996 | Fremont | USA | Left | Left | 5' 10" | 175 lbs | - |
| Stewart, Brock | SP | Scranton WB RailRiders | 29 | 10/03/1991 | Normal | USA | Left | Right | 6' 3" | 215 lbs | $545,000 |
| Stewart, Christin | LF | New Orleans Baby Cakes | 26 | 12/10/1993 | Lawrenceville | USA | Left | Right | 6' 0" | 205 lbs | $545,000 |
| Stewart, DJ | LF | El Paso Chihuahuas | 26 | 11/30/1993 | Yulee | USA | Left | Right | 6' 0" | 230 lbs | $1,200,000 |
| Stewart, Kohl | RP | Norfolk Tides | 26 | 10/07/1994 | Tomball | USA | Right | Right | 6' 3" | 195 lbs | $850,000 |
| Stokes Jr., Troy | LF | Pawtucket Red Sox | 24 | 02/02/1996 | Baltimore | USA | Right | Right | 5' 8" | 180 lbs | - |
| Stowers, Kyle | RF | Colorado Springs Sky Sox | 22 | 01/02/1998 | El Cajon | USA | Left | Left | 6' 3" | 200 lbs | - |
| Strahan, Wyatt | RP | Syracuse Chiefs | 27 | 04/18/1993 | Villa Park | USA | Right | Right | 6' 3" | 220 lbs | - |
| Stumpf, Daniel | CL | New Orleans Baby Cakes | 29 | 01/04/1991 | Humble | USA | Left | Left | 6' 2" | 210 lbs | - |
| Suarez, Andrew | SP | New Orleans Baby Cakes | 28 | 09/11/1992 | Miami | USA | Left | Left | 6' 0" | 185 lbs | - |
| Sucre, Jesus | C | Free Agent | 32 | 04/30/1988 | Cumana | VEN | Right | Right | 6' 0" | 200 lbs | - |
| Sullivan, Brett | C | Lehigh Valley IronPigs | 26 | 02/22/1994 | Stockton | USA | Left | Right | 6' 1" | 195 lbs | $545,000 |
| Sulser, Cole | CL | Gwinnett Stripers | 30 | 03/12/1990 | San Diego | USA | Right | Right | 6' 1" | 190 lbs | - |
| Swarmer, Matt | RP | Albuquerque Isotopes | 27 | 09/25/1993 | Mohnton | USA | Right | Right | 6' 5" | 195 lbs | - |
| Swarzak, Anthony | RP | Memphis Redbirds | 35 | 09/10/1985 | Ft. Lauderdale | USA | Right | Right | 6' 4" | 215 lbs | - |
| Szapucki, Thomas | RP | Reno Aces | 24 | 06/12/1996 | Palm Beach Gardens | USA | Right | Left | 6' 2" | 180 lbs | - |
| Szczur, Matt | LF | Toledo Mud Hens | 31 | 07/20/1989 | Cape May | USA | Right | Right | 6' 0" | 200 lbs | - |
