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| Position | Top player | Team ranking | Top prospect | Organizational ranking | Overall ranking |
|---|---|---|---|---|---|
| Catchers | Sean Murphy | 9th | Sam Huff | 1st | 5th |
| First Basemen | Anthony Rizzo | 1st | Triston Casas | Tied for 13th | 2nd |
| Second Basemen | Howie Kendrick | 12th | Hyo-jun Park | 30th | 29th |
| Third Basemen | Nolan Arenado | 1st | Jonathan Ornelas | Tied for 28th | 23rd |
| Shortstops | Dansby Swanson | 19th | Eduardo Garcia | 15th | 16th |
| Left Fielders | Jesse Winker | 12th | Desmond Lindsay | 20th | 12th |
| Center Fielders | Manuel Margot | 20th | Jeremy De La Rosa | Tied for 14th | 19th |
| Right Fielders | Trent Grisham | 11th | Riley Greene | Tied for 23rd | 11th |
| Starting Pitchers | Charlie Morton | 3rd | Enoli Paredes | Tied for 16th | 10th |
| Relievers | Jose Alvarado | 8th | Blake Cederlind | 18th | 8th |
| Closers | Taylor Guilbeau | 9th | Kyle Dohy | Tied for 11th | 5th |
