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| Name | W | L | SV | ERA | G | GS | IP | HA | R | ER | HR | BB | K | WHIP | OAVG | BABIP | WAR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Richard Rodriguez RP | 0 | 0 | 0 | 0.00 | 6 | 0 | 5.2 | 1 | 0 | 0 | 0 | 1 | 5 | 0.35 | .056 | .077 | 0.2 |
| Justus Sheffield RP | 0 | 0 | 1 | 0.81 | 24 | 0 | 33.1 | 23 | 3 | 3 | 1 | 10 | 36 | 0.99 | .192 | .265 | 1.1 |
| Junior Fernandez SP | 1 | 0 | 0 | 1.17 | 4 | 0 | 7.2 | 5 | 1 | 1 | 0 | 1 | 12 | 0.78 | .192 | .333 | 0.4 |
| Danny Salazar SP | 19 | 7 | 0 | 2.72 | 34 | 34 | 205.0 | 166 | 66 | 62 | 32 | 52 | 225 | 1.06 | .216 | .262 | 4.0 |
| Bruce Rondon RP | 0 | 2 | 1 | 2.81 | 27 | 0 | 32.0 | 15 | 10 | 10 | 4 | 28 | 44 | 1.34 | .146 | .193 | -0.1 |
| Will Vest RP | 1 | 0 | 1 | 3.38 | 30 | 0 | 29.1 | 22 | 13 | 11 | 4 | 17 | 48 | 1.33 | .204 | .321 | 0.4 |
| Daniel Norris RP | 6 | 5 | 0 | 3.38 | 34 | 18 | 122.2 | 99 | 53 | 46 | 20 | 40 | 104 | 1.13 | .219 | .239 | 0.8 |
| Patrick Dayton RP | 4 | 2 | 1 | 3.53 | 47 | 0 | 51.0 | 38 | 21 | 20 | 3 | 18 | 69 | 1.10 | .204 | .302 | 1.5 |
| Drew Smyly SP | 12 | 8 | 2 | 3.54 | 41 | 24 | 168.0 | 130 | 75 | 66 | 36 | 59 | 173 | 1.13 | .211 | .229 | 0.7 |
| Blake Snell SP | 12 | 12 | 0 | 3.55 | 34 | 34 | 205.1 | 178 | 95 | 81 | 36 | 78 | 246 | 1.25 | .230 | .287 | 3.0 |
| Oscar De La Cruz SP | 0 | 1 | 0 | 3.60 | 2 | 2 | 10.0 | 6 | 4 | 4 | 0 | 2 | 10 | 0.80 | .182 | .240 | 0.3 |
| Rex Brothers CL | 4 | 8 | 37 | 3.61 | 59 | 0 | 62.1 | 33 | 25 | 25 | 6 | 51 | 130 | 1.35 | .151 | .325 | 2.1 |
| Raisel Iglesias RP | 6 | 1 | 6 | 3.63 | 70 | 0 | 69.1 | 49 | 31 | 28 | 14 | 26 | 103 | 1.08 | .191 | .248 | 0.6 |
| Dylan Cease SP | 3 | 5 | 1 | 3.90 | 34 | 12 | 85.1 | 68 | 38 | 37 | 11 | 32 | 100 | 1.17 | .213 | .273 | 1.4 |
| Dallas Keuchel SP | 10 | 11 | 0 | 4.18 | 32 | 32 | 183.0 | 179 | 87 | 85 | 32 | 49 | 126 | 1.25 | .254 | .268 | 1.2 |
| Felix Hernandez SP | 5 | 3 | 0 | 4.48 | 33 | 4 | 66.1 | 75 | 42 | 33 | 10 | 29 | 28 | 1.57 | .294 | .295 | -0.7 |
| Ryan Sherriff RP | 1 | 4 | 0 | 4.64 | 35 | 0 | 33.0 | 33 | 19 | 17 | 8 | 8 | 32 | 1.24 | .252 | .272 | -0.3 |
| Edgar Santana RP | 3 | 0 | 1 | 4.91 | 25 | 0 | 25.2 | 18 | 14 | 14 | 4 | 7 | 28 | 0.97 | .189 | .222 | 0.2 |
| Jared Hughes RP | 0 | 1 | 0 | 5.00 | 9 | 0 | 9.0 | 13 | 5 | 5 | 0 | 5 | 11 | 2.00 | .351 | .500 | 0.2 |
| Sal Romano SP | 2 | 2 | 2 | 5.26 | 34 | 0 | 51.1 | 50 | 34 | 30 | 13 | 17 | 46 | 1.31 | .245 | .253 | -0.6 |
| Tyler Duffey CL | 0 | 1 | 0 | 20.77 | 2 | 2 | 4.1 | 9 | 10 | 10 | 3 | 3 | 4 | 2.77 | .429 | .429 | -0.3 |
